Cargando…
Aurora kinase A in gastrointestinal cancers: time to target
Gastrointestinal (GI) cancers are a major cause of cancer-related deaths. During the last two decades, several studies have shown amplification and overexpression of Aurora kinase A (AURKA) in several GI malignancies. These studies demonstrated that AURKA not only plays a role in regulating cell cyc...
Autores principales: | Katsha, Ahmed, Belkhiri, Abbes, Goff, Laura, El-Rifai, Wael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436812/ https://www.ncbi.nlm.nih.gov/pubmed/25987188 http://dx.doi.org/10.1186/s12943-015-0375-4 |
Ejemplares similares
-
Cisplatin‐resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib
por: Wang, Lihong, et al.
Publicado: (2017) -
The Aurora kinase A Regulates GSK-3β in Gastric Cancer Cells
por: Dar, Altaf A, et al.
Publicado: (2008) -
Advances in targeted therapies and new promising targets in esophageal cancer
por: Belkhiri, Abbes, et al.
Publicado: (2015) -
Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis
por: Zhu, Shoumin, et al.
Publicado: (2015) -
TFF1 activates p53 through down-regulation of miR-504 in gastric cancer
por: Soutto, Mohammed, et al.
Publicado: (2014)