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Therapeutic aptamers: developmental potential as anticancer drugs
Aptamers, composed of single-stranded DNA or RNA oligonucleotides that interact with target molecules through a specific three-dimensional structure, are selected from pools of combinatorial oligonucleotide libraries. With their high specificity and affinity for target proteins, ease of synthesis an...
Autores principales: | Lee, Ji Won, Kim, Hyun Jung, Heo, Kyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436860/ https://www.ncbi.nlm.nih.gov/pubmed/25560701 http://dx.doi.org/10.5483/BMBRep.2015.48.4.277 |
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