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Cooperation of Hsp70 and Hsp100 chaperone machines in protein disaggregation
Unicellular and sessile organisms are particularly exposed to environmental stress such as heat shock causing accumulation and aggregation of misfolded protein species. To counteract protein aggregation, bacteria, fungi, and plants encode a bi-chaperone system composed of ATP-dependent Hsp70 and hex...
Autores principales: | Mogk, Axel, Kummer, Eva, Bukau, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436881/ https://www.ncbi.nlm.nih.gov/pubmed/26042222 http://dx.doi.org/10.3389/fmolb.2015.00022 |
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