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Nanoparticle mediated drug delivery of rolipram to tyrosine kinase B positive cells in the inner ear with targeting peptides and agonistic antibodies
Aim: Systemic pharmacotherapies have limitation due to blood-labyrinth barrier, so local delivery via the round window membrane opens a path for effective treatment. Multifunctional nanoparticle (NP)-mediated cell specific drug delivery may enhance efficacy and reduce side effects. Different NPs wit...
Autores principales: | Glueckert, Rudolf, Pritz, Christian O., Roy, Soumen, Dudas, Jozsef, Schrott-Fischer, Anneliese |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436893/ https://www.ncbi.nlm.nih.gov/pubmed/26042029 http://dx.doi.org/10.3389/fnagi.2015.00071 |
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