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Low-dose add-on memantine treatment may improve cognitive performance and self-reported health conditions in opioid-dependent patients undergoing methadone-maintenance-therapy
An important interaction between opioid and dopamine systems has been indicated, and using opioids may negatively affect cognitive functioning. Memantine, a medication for Alzheimer's disease, increasingly is being used for several disorders and maybe important for cognitive improvement. Opioid...
Autores principales: | Chang, Yun-Hsuan, Chen, Shiou-Lan, Lee, Sheng-Yu, Chen, Po See, Wang, Tzu-Yun, Lee, I. Hui, Chen, Kao Chin, Yang, Yen Kuang, Hong, Jau-Shyong, Lu, Ru-Band |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437025/ https://www.ncbi.nlm.nih.gov/pubmed/25989606 http://dx.doi.org/10.1038/srep09708 |
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