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Functional Epigenetic Analysis of Prostate Carcinoma: A Role for Seryl-tRNA Synthetase?

Transcriptional silencing, as a result of aberrant promoter hypermethylation, is a common mechanism through which genes in cancer cells become inactive. Functional epigenetic screens using demethylating agents to reexpress transcriptional silenced genes may identify such inactivated genes for needin...

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Detalles Bibliográficos
Autores principales: Ikromov, Odiljon, Alkamal, Imad, Magheli, Ahmed, Ratert, Nadine, Sendeski, Mauricio, Miller, Kurt, Krause, Hans, Kempkensteffen, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437382/
https://www.ncbi.nlm.nih.gov/pubmed/26317032
http://dx.doi.org/10.1155/2014/362164