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Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma

BACKGROUND: Survivin is a small protein inhibitor of apoptosis and a tumor associated antigen. Survivin expression in multiple myeloma is associated with poor prognosis, disease progression, and drug resistance. The CD4+ response against survivin remains uncharacterized. METHODS: In order to better...

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Detalles Bibliográficos
Autores principales:	Locke, Frederick L, Menges, Meghan, Veerapathran, Anandharaman, Coppola, Domenico, Gabrilovich, Dmitry, Anasetti, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437443/ https://www.ncbi.nlm.nih.gov/pubmed/25992291 http://dx.doi.org/10.1186/s40425-015-0065-1

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