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A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) gene and systemic sclerosis

INTRODUCTION: The multifunctional nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ) has potent anti-fibrotic effects, and its expression and activity are impaired in patients with systemic sclerosis (SSc). We investigated PPAR-γ gene (PPARG) single nucleotide polymorphisms (...

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Detalles Bibliográficos
Autores principales:	Marangoni, Roberta Goncalves, Korman, Benjamin D, Allanore, Yannick, Dieude, Philippe, Armstrong, Loren L, Rzhetskaya, Margarita, Hinchcliff, Monique, Carns, Mary, Podlusky, Sofia, Shah, Sanjiv J, Ruiz, Barbara, Hachulla, Eric, Tiev, Kiet, Cracowski, Jean-Luc, Varga, John, Hayes, M Geoffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437446/ https://www.ncbi.nlm.nih.gov/pubmed/25986483 http://dx.doi.org/10.1186/s13075-015-0641-2

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