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Small-Molecule-Driven Hepatocyte Differentiation of Human Pluripotent Stem Cells
The differentiation of pluripotent stem cells to hepatocytes is well established, yet current methods suffer from several drawbacks. These include a lack of definition and reproducibility, which in part stems from continued reliance on recombinant growth factors. This has remained a stumbling block...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437467/ https://www.ncbi.nlm.nih.gov/pubmed/25937370 http://dx.doi.org/10.1016/j.stemcr.2015.04.001 |