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Small-Molecule-Driven Hepatocyte Differentiation of Human Pluripotent Stem Cells

The differentiation of pluripotent stem cells to hepatocytes is well established, yet current methods suffer from several drawbacks. These include a lack of definition and reproducibility, which in part stems from continued reliance on recombinant growth factors. This has remained a stumbling block...

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Detalles Bibliográficos
Autores principales: Siller, Richard, Greenhough, Sebastian, Naumovska, Elena, Sullivan, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437467/
https://www.ncbi.nlm.nih.gov/pubmed/25937370
http://dx.doi.org/10.1016/j.stemcr.2015.04.001