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Castration-Resistant Lgr5(+) Cells Are Long-Lived Stem Cells Required for Prostatic Regeneration
The adult prostate possesses a significant regenerative capacity that is of great interest for understanding adult stem cell biology. We demonstrate that leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5) is expressed in a rare population of prostate epithelial progenitor cells, and...
Autores principales: | Wang, Bu-er, Wang, Xi, Long, Jason E., Eastham-Anderson, Jeff, Firestein, Ron, Junttila, Melissa R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437474/ https://www.ncbi.nlm.nih.gov/pubmed/25937372 http://dx.doi.org/10.1016/j.stemcr.2015.04.003 |
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