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Elimination of Tumorigenic Human Pluripotent Stem Cells by a Recombinant Lectin-Toxin Fusion Protein
The application of stem-cell-based therapies in regenerative medicine is hindered by the tumorigenic potential of residual human pluripotent stem cells. Previously, we identified a human pluripotent stem-cell-specific lectin probe, called rBC2LCN, by comprehensive glycome analysis using high-density...
Autores principales: | Tateno, Hiroaki, Onuma, Yasuko, Ito, Yuzuru, Minoshima, Fumi, Saito, Sayoko, Shimizu, Madoka, Aiki, Yasuhiko, Asashima, Makoto, Hirabayashi, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437484/ https://www.ncbi.nlm.nih.gov/pubmed/25866158 http://dx.doi.org/10.1016/j.stemcr.2015.02.016 |
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