Cargando…
SOX2 Reprograms Resident Astrocytes into Neural Progenitors in the Adult Brain
Glial cells can be in vivo reprogrammed into functional neurons in the adult CNS; however, the process by which this reprogramming occurs is unclear. Here, we show that a distinct cellular sequence is involved in SOX2-driven in situ conversion of adult astrocytes to neurons. This includes ASCL1(+) n...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437485/ https://www.ncbi.nlm.nih.gov/pubmed/25921813 http://dx.doi.org/10.1016/j.stemcr.2015.03.006 |