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Aging increases microglial proliferation, delays cell migration, and decreases cortical neurogenesis after focal cerebral ischemia

BACKGROUND: Aging is not just a risk factor of stroke, but it has also been associated with poor recovery. It is known that stroke-induced neurogenesis is reduced but maintained in the aged brain. However, there is no consensus on how neurogenesis is affected after stroke in aged animals. Our object...

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Detalles Bibliográficos
Autores principales: Moraga, Ana, Pradillo, Jesús M, García-Culebras, Alicia, Palma-Tortosa, Sara, Ballesteros, Ivan, Hernández-Jiménez, Macarena, Moro, María A, Lizasoain, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437744/
https://www.ncbi.nlm.nih.gov/pubmed/25958332
http://dx.doi.org/10.1186/s12974-015-0314-8