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Endothelin Receptors and Their Antagonists()()
All three members of the endothelin (ET) family of peptides, ET-1, ET-2, and ET-3, are expressed in the human kidney, with ET-1 being the predominant isoform. ET-1 and ET-2 bind to two G-protein–coupled receptors, ET(A) and ET(B), whereas at physiological concentrations ET-3 has little affinity for...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
W.B. Saunders
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437774/ https://www.ncbi.nlm.nih.gov/pubmed/25966344 http://dx.doi.org/10.1016/j.semnephrol.2015.02.002 |