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Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects

Autotaxin (ATX) is a secretory protein, which converts lysophospholipids to lysophosphatidic acid (LPA), and is essential for embryonic vascular formation. ATX is abundantly detected in various biological fluids and its level is elevated in some pathophysiological conditions. However, the roles of e...

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Detalles Bibliográficos
Autores principales: Yukiura, Hiroshi, Kano, Kuniyuki, Kise, Ryoji, Inoue, Asuka, Aoki, Junken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438000/
https://www.ncbi.nlm.nih.gov/pubmed/25992708
http://dx.doi.org/10.1371/journal.pone.0126734

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