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Eculizumab and drug-induced haemolytic–uraemic syndrome

The monoclonal anti-C5 antibody eculizumab has been successfully tested in atypical haemolytic-uraemic syndrome (aHUS), with or without mutations in the regulatory proteins of the alternative pathway of the complement, and less convincingly in enterohaemorrhagic Escherichia coli-associated HUS. Here...

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Detalles Bibliográficos
Autores principales:	Faguer, Stanislas, Huart, Antoine, Frémeaux-Bacchi, Véronique, Ribes, David, Chauveau, Dominique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Original Contributions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438394/ https://www.ncbi.nlm.nih.gov/pubmed/26120441 http://dx.doi.org/10.1093/ckj/sft078

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