Mineralocorticoid receptor blockade—a novel approach to fight hyperkalaemia in chronic kidney disease

Hyperkalaemia continues to be a major hazard of mineralocorticoid receptor blockade in an effort to retard the progression of chronic kidney disease (CKD). In cardiac patients on mineralocorticoid receptor blockade, RLY-5016 which captures K(+) in the colon has been effective in reducing the risk of...

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Detalles Bibliográficos
Autores principales: Ritz, E., Pitt, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438399/
https://www.ncbi.nlm.nih.gov/pubmed/26120440
http://dx.doi.org/10.1093/ckj/sft084
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author Ritz, E.
Pitt, B.
author_facet Ritz, E.
Pitt, B.
author_sort Ritz, E.
collection PubMed
description Hyperkalaemia continues to be a major hazard of mineralocorticoid receptor blockade in an effort to retard the progression of chronic kidney disease (CKD). In cardiac patients on mineralocorticoid receptor blockade, RLY-5016 which captures K(+) in the colon has been effective in reducing the risk of hyperkalaemia. This compound might be useful in CKD as well.
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spelling pubmed-44383992015-06-26 Mineralocorticoid receptor blockade—a novel approach to fight hyperkalaemia in chronic kidney disease Ritz, E. Pitt, B. Clin Kidney J Original Contributions Hyperkalaemia continues to be a major hazard of mineralocorticoid receptor blockade in an effort to retard the progression of chronic kidney disease (CKD). In cardiac patients on mineralocorticoid receptor blockade, RLY-5016 which captures K(+) in the colon has been effective in reducing the risk of hyperkalaemia. This compound might be useful in CKD as well. Oxford University Press 2013-10 2013-09-01 /pmc/articles/PMC4438399/ /pubmed/26120440 http://dx.doi.org/10.1093/ckj/sft084 Text en © The Author 2013. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please email: journals.permissions@oup.com. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Contributions
Ritz, E.
Pitt, B.
Mineralocorticoid receptor blockade—a novel approach to fight hyperkalaemia in chronic kidney disease
title Mineralocorticoid receptor blockade—a novel approach to fight hyperkalaemia in chronic kidney disease
title_full Mineralocorticoid receptor blockade—a novel approach to fight hyperkalaemia in chronic kidney disease
title_fullStr Mineralocorticoid receptor blockade—a novel approach to fight hyperkalaemia in chronic kidney disease
title_full_unstemmed Mineralocorticoid receptor blockade—a novel approach to fight hyperkalaemia in chronic kidney disease
title_short Mineralocorticoid receptor blockade—a novel approach to fight hyperkalaemia in chronic kidney disease
title_sort mineralocorticoid receptor blockade—a novel approach to fight hyperkalaemia in chronic kidney disease
topic Original Contributions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438399/
https://www.ncbi.nlm.nih.gov/pubmed/26120440
http://dx.doi.org/10.1093/ckj/sft084
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AT pittb mineralocorticoidreceptorblockadeanovelapproachtofighthyperkalaemiainchronickidneydisease

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