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Frequency of coreceptor tropism in PBMC samples from HIV-1 recently infected blood donors by massively parallel sequencing: the REDS II study

BACKGROUND: The interaction of HIV-1 and target cells involves sequential binding of the viral gp120 Env protein to the CD4 receptor and a chemokine co-receptor (either CCR5 or CXCR4). CCR5 antagonists have proved to be an effective salvage therapy in patients with CCR5 using variants (R5) but not w...

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Detalles Bibliográficos
Autores principales:	Pessôa, Rodrigo, Sabino, Ester C, Sanabani, Sabri S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438479/ https://www.ncbi.nlm.nih.gov/pubmed/25966986 http://dx.doi.org/10.1186/s12985-015-0307-3

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