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Primate Phencyclidine Model of Schizophrenia: Sex-Specific Effects on Cognition, Brain Derived Neurotrophic Factor, Spine Synapses, and Dopamine Turnover in Prefrontal Cortex

BACKGROUND: Cognitive deficits are a core symptom of schizophrenia, yet they remain particularly resistant to treatment. The model provided by repeatedly exposing adult nonhuman primates to phencyclidine has generated important insights into the neurobiology of these deficits, but it remains possibl...

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Detalles Bibliográficos
Autores principales:	Elsworth, John D., Groman, Stephanie M., Jentsch, James D., Leranth, Csaba, Redmond, D. Eugene, Kim, Jung D., Diano, Sabrina, Roth, Robert H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438537/ https://www.ncbi.nlm.nih.gov/pubmed/25522392 http://dx.doi.org/10.1093/ijnp/pyu048

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