Enhanced expression of cohesin loading factor NIPBL confers poor prognosis and chemotherapy resistance in non-small cell lung cancer

BACKGROUND: NIPBL, the sister chromatid cohesion 2 (SCC2) human homolog, is a cohesin loading factor which is essential for deposition of cohesin onto the sister chromatid. Recent studies have shown that NIPBL contribute to sister chromatid cohesion and plays a critical role in development, DNA repa...

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Detalles Bibliográficos
Autores principales: Xu, Weizhen, Ying, Yinyin, Shan, Lihong, Feng, Jianguo, Zhang, Shengjie, Gao, Yun, Xu, Xiaoling, Yao, Yinli, Zhu, Chihong, Mao, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438579/
https://www.ncbi.nlm.nih.gov/pubmed/25963978
http://dx.doi.org/10.1186/s12967-015-0503-3

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