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The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial

Cocoa supplementation has been associated with benefits to cardiovascular health. However, cocoa's effects on cognition are less clear. A randomized, placebo-controlled, double-blind clinical trial (n = 40, age M = 24.13 years, SD = 4.47 years) was conducted to investigate the effects of both a...

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Autores principales: Massee, Laura A., Ried, Karin, Pase, Matthew, Travica, Nikolaj, Yoganathan, Jaesshanth, Scholey, Andrew, Macpherson, Helen, Kennedy, Greg, Sali, Avni, Pipingas, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438591/
https://www.ncbi.nlm.nih.gov/pubmed/26042037
http://dx.doi.org/10.3389/fphar.2015.00093
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author Massee, Laura A.
Ried, Karin
Pase, Matthew
Travica, Nikolaj
Yoganathan, Jaesshanth
Scholey, Andrew
Macpherson, Helen
Kennedy, Greg
Sali, Avni
Pipingas, Andrew
author_facet Massee, Laura A.
Ried, Karin
Pase, Matthew
Travica, Nikolaj
Yoganathan, Jaesshanth
Scholey, Andrew
Macpherson, Helen
Kennedy, Greg
Sali, Avni
Pipingas, Andrew
author_sort Massee, Laura A.
collection PubMed
description Cocoa supplementation has been associated with benefits to cardiovascular health. However, cocoa's effects on cognition are less clear. A randomized, placebo-controlled, double-blind clinical trial (n = 40, age M = 24.13 years, SD = 4.47 years) was conducted to investigate the effects of both acute (same-day) and sub-chronic (daily for four-weeks) 250 mg cocoa supplementation on mood and mental fatigue, cognitive performance and cardiovascular functioning in young, healthy adults. Assessment involved repeated 10-min cycles of the Cognitive Demand Battery (CDB) encompassing two serial subtraction tasks (Serial Threes and Sevens), a Rapid Visual Information Processing task, and a mental fatigue scale over the course of half an hour. The Swinburne University Computerized Cognitive Assessment Battery (SUCCAB) was also completed to evaluate cognition. Cardiovascular function included measuring both peripheral and central blood pressure and cerebral blood flow. At the acute time point, consumption of cocoa significantly improved self-reported mental fatigue and performance on the Serial Sevens task in cycle one of the CDB. No other significant effects were found. This trial was registered with the Australian and New Zealand Clinical Trial Registry (Trial ID: ACTRN12613000626763). Accessible via http://www.anzctr.org.au/TrialSearch.aspx?searchTxt=ACTRN12613000626763&ddlSearch=Registered.
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spelling pubmed-44385912015-06-03 The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial Massee, Laura A. Ried, Karin Pase, Matthew Travica, Nikolaj Yoganathan, Jaesshanth Scholey, Andrew Macpherson, Helen Kennedy, Greg Sali, Avni Pipingas, Andrew Front Pharmacol Pharmacology Cocoa supplementation has been associated with benefits to cardiovascular health. However, cocoa's effects on cognition are less clear. A randomized, placebo-controlled, double-blind clinical trial (n = 40, age M = 24.13 years, SD = 4.47 years) was conducted to investigate the effects of both acute (same-day) and sub-chronic (daily for four-weeks) 250 mg cocoa supplementation on mood and mental fatigue, cognitive performance and cardiovascular functioning in young, healthy adults. Assessment involved repeated 10-min cycles of the Cognitive Demand Battery (CDB) encompassing two serial subtraction tasks (Serial Threes and Sevens), a Rapid Visual Information Processing task, and a mental fatigue scale over the course of half an hour. The Swinburne University Computerized Cognitive Assessment Battery (SUCCAB) was also completed to evaluate cognition. Cardiovascular function included measuring both peripheral and central blood pressure and cerebral blood flow. At the acute time point, consumption of cocoa significantly improved self-reported mental fatigue and performance on the Serial Sevens task in cycle one of the CDB. No other significant effects were found. This trial was registered with the Australian and New Zealand Clinical Trial Registry (Trial ID: ACTRN12613000626763). Accessible via http://www.anzctr.org.au/TrialSearch.aspx?searchTxt=ACTRN12613000626763&ddlSearch=Registered. Frontiers Media S.A. 2015-05-20 /pmc/articles/PMC4438591/ /pubmed/26042037 http://dx.doi.org/10.3389/fphar.2015.00093 Text en Copyright © 2015 Massee, Ried, Pase, Travica, Yoganathan, Scholey, Macpherson, Kennedy, Sali and Pipingas. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Massee, Laura A.
Ried, Karin
Pase, Matthew
Travica, Nikolaj
Yoganathan, Jaesshanth
Scholey, Andrew
Macpherson, Helen
Kennedy, Greg
Sali, Avni
Pipingas, Andrew
The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial
title The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial
title_full The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial
title_fullStr The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial
title_full_unstemmed The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial
title_short The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial
title_sort acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438591/
https://www.ncbi.nlm.nih.gov/pubmed/26042037
http://dx.doi.org/10.3389/fphar.2015.00093
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