Intratumoral injection of IFN-alpha dendritic cells after dacarbazine activates anti-tumor immunity: results from a phase I trial in advanced melanoma

BACKGROUND: Advanced melanoma patients have an extremely poor long term prognosis and are in strong need of new therapies. The recently developed targeted therapies have resulted in a marked antitumor effect, but most responses are partial and some degree of toxicity remain the major concerns. Dendr...

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Detalles Bibliográficos
Autores principales: Rozera, Carmela, Cappellini, Giancarlo Antonini, D’Agostino, Giuseppina, Santodonato, Laura, Castiello, Luciano, Urbani, Francesca, Macchia, Iole, Aricò, Eleonora, Casorelli, Ida, Sestili, Paola, Montefiore, Enrica, Monque, Domenica, Carlei, Davide, Napolitano, Mariarosaria, Rizza, Paola, Moschella, Federica, Buccione, Carla, Belli, Roberto, Proietti, Enrico, Pavan, Antonio, Marchetti, Paolo, Belardelli, Filippo, Capone, Imerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438625/
https://www.ncbi.nlm.nih.gov/pubmed/25933939
http://dx.doi.org/10.1186/s12967-015-0473-5

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