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Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice

The critical period is a distinct time-window during the neonatal stage when animals display elevated sensitivity to certain environmental stimuli, and particular experiences can have profound and long-lasting effects on behaviors. Increasing evidence suggests that disruption of neuronal activity du...

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Detalles Bibliográficos
Autores principales: Yufune, Shinya, Satoh, Yasushi, Takamatsu, Isao, Ohta, Hiroyuki, Kobayashi, Yasushi, Takaenoki, Yumiko, Pagès, Gilles, Pouysségur, Jacques, Endo, Shogo, Kazama, Tomiei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438718/
https://www.ncbi.nlm.nih.gov/pubmed/25993696
http://dx.doi.org/10.1038/srep10252