Application of RNAi to Genomic Drug Target Validation in Schistosomes

Concerns over the possibility of resistance developing to praziquantel (PZQ), has stimulated efforts to develop new drugs for schistosomiasis. In addition to the development of improved whole organism screens, the success of RNA interference (RNAi) in schistosomes offers great promise for the identi...

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Detalles Bibliográficos
Autores principales: Guidi, Alessandra, Mansour, Nuha R., Paveley, Ross A., Carruthers, Ian M., Besnard, Jérémy, Hopkins, Andrew L., Gilbert, Ian H., Bickle, Quentin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438872/
https://www.ncbi.nlm.nih.gov/pubmed/25992548
http://dx.doi.org/10.1371/journal.pntd.0003801

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