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All-trans retinoic acid impairs the vasculogenic mimicry formation ability of U87 stem-like cells through promoting differentiation

The poor therapeutic effect of traditional antiangiogenic therapy on glioblastoma multiforme (GBM) may be attributed to vasculogenic mimicry (VM), which was previously reported to be promoted by cancer stem-like cells (SLCs). All-trans retinoic acid (ATRA), a potent reagent which drives differentiat...

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Detalles Bibliográficos
Autores principales: LING, GENG-QIANG, LIU, YI-JING, KE, YI-QUAN, CHEN, LEI, JIANG, XIAO-DAN, JIANG, CHUAN-LU, YE, WEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438921/
https://www.ncbi.nlm.nih.gov/pubmed/25760394
http://dx.doi.org/10.3892/mmr.2015.3449