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Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes

[Image: see text] Cells respond to stress by controlling gene expression at several levels, with little known about the role of translation. Here, we demonstrate a coordinated translational stress response system involving stress-specific reprogramming of tRNA wobble modifications that leads to sele...

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Detalles Bibliográficos
Autores principales: Chan, Clement T. Y., Deng, Wenjun, Li, Fugen, DeMott, Michael S., Babu, I. Ramesh, Begley, Thomas J., Dedon, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438938/
https://www.ncbi.nlm.nih.gov/pubmed/25772370
http://dx.doi.org/10.1021/acs.chemrestox.5b00004