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Hepatitis B Virus X Protein Sensitizes TRAIL-Induced Hepatocyte Apoptosis by Inhibiting the E3 Ubiquitin Ligase A20
Hepatitis B virus (HBV) infection causes hepatocyte death and liver damage, which may eventually lead to cirrhosis and liver cancer. Hepatitis B virus X protein (HBx) is a key antigen that is critically involved in HBV-associated liver diseases. However, the molecular basis for its pathogenesis, par...
Autores principales: | Zhang, Hang, Huang, Changxin, Wang, Yan, Lu, Zhe, Zhuang, Ningtong, Zhao, Dongjiu, He, Jianqin, Shi, Liyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439114/ https://www.ncbi.nlm.nih.gov/pubmed/25993287 http://dx.doi.org/10.1371/journal.pone.0127329 |
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