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Hepatitis B Virus X Protein Sensitizes TRAIL-Induced Hepatocyte Apoptosis by Inhibiting the E3 Ubiquitin Ligase A20

Hepatitis B virus (HBV) infection causes hepatocyte death and liver damage, which may eventually lead to cirrhosis and liver cancer. Hepatitis B virus X protein (HBx) is a key antigen that is critically involved in HBV-associated liver diseases. However, the molecular basis for its pathogenesis, par...

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Detalles Bibliográficos
Autores principales: Zhang, Hang, Huang, Changxin, Wang, Yan, Lu, Zhe, Zhuang, Ningtong, Zhao, Dongjiu, He, Jianqin, Shi, Liyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439114/
https://www.ncbi.nlm.nih.gov/pubmed/25993287
http://dx.doi.org/10.1371/journal.pone.0127329

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