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Histone Demethylation Maintains Prdm14 and Tsix Expression and Represses Xist in Embryonic Stem Cells

Epigenetic reprogramming is exemplified by the remarkable changes observed in cellular differentiation and X-chromosome inactivation (XCI) in mammalian female cells. Histone 3 lysine 27 trimethylation (H3K27me3) is a modification that suppresses gene expression in multiple contexts including embryon...

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Detalles Bibliográficos
Autores principales: Kamikawa, Yasunao F., Donohoe, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439117/
https://www.ncbi.nlm.nih.gov/pubmed/25993097
http://dx.doi.org/10.1371/journal.pone.0125626

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