Cargando…

Human cytomegalovirus: taking the strain

In celebrating the 60th anniversary of the first isolation of human cytomegalovirus (HCMV), we reflect on the merits and limitations of the viral strains currently being used to develop urgently needed treatments. HCMV research has been dependent for decades on the high-passage strains AD169 and Tow...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wilkinson, Gavin W. G., Davison, Andrew J., Tomasec, Peter, Fielding, Ceri A., Aicheler, Rebecca, Murrell, Isa, Seirafian, Sepher, Wang, Edward C. Y., Weekes, Michael, Lehner, Paul J., Wilkie, Gavin S., Stanton, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439430/ https://www.ncbi.nlm.nih.gov/pubmed/25894764 http://dx.doi.org/10.1007/s00430-015-0411-4

Ejemplares similares

Genetic Stability of Bacterial Artificial Chromosome-Derived Human Cytomegalovirus during Culture In Vitro
por: Murrell, Isa, et al.
Publicado: (2016)

Impact of Sequence Variation in the UL128 Locus on Production of Human Cytomegalovirus in Fibroblast and Epithelial Cells
por: Murrell, Isa, et al.
Publicado: (2013)

Quantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction
por: Weekes, Michael P., et al.
Publicado: (2014)

Human cytomegalovirus suppresses Fas expression and function
por: Seirafian, Sepehr, et al.
Publicado: (2014)

Two Novel Human Cytomegalovirus NK Cell Evasion Functions Target MICA for Lysosomal Degradation
por: Fielding, Ceri A., et al.
Publicado: (2014)

Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation
por: Fielding, Ceri A, et al.
Publicado: (2017)

Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus
por: Vlahava, Virginia-Maria, et al.
Publicado: (2021)

Plasma Membrane Profiling Defines an Expanded Class of Cell Surface Proteins Selectively Targeted for Degradation by HCMV US2 in Cooperation with UL141
por: Hsu, Jye-Lin, et al.
Publicado: (2015)

HCMV pUL135 Remodels the Actin Cytoskeleton to Impair Immune Recognition of Infected Cells
por: Stanton, Richard J., et al.
Publicado: (2014)

Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions
por: Nobre, Luis V, et al.
Publicado: (2019)

High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms
por: Nightingale, Katie, et al.
Publicado: (2018)

ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways
por: Rubina, Anzelika, et al.
Publicado: (2023)

Adenovirus vector delivery stimulates natural killer cell recognition
por: Tomasec, Peter, et al.
Publicado: (2007)

Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture
por: Dargan, Derrick J., et al.
Publicado: (2010)

Human Cytomegalovirus Glycoprotein UL141 Targets the TRAIL Death Receptors to Thwart Host Innate Antiviral Defenses
por: Smith, Wendell, et al.
Publicado: (2013)

Human cytomegalovirus UL141 promotes efficient downregulation of the natural killer cell activating ligand CD112
por: Prod'homme, Virginie, et al.
Publicado: (2010)

Strain-Dependent Restriction of Human Cytomegalovirus by Zinc Finger Antiviral Proteins
por: Lista, Maria Jose, et al.
Publicado: (2023)

High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169
por: Bradley, Amanda J., et al.
Publicado: (2009)

Downregulation of HLA-I by the molluscum contagiosum virus mc080 impacts NK-cell recognition and promotes CD8(+) T-cell evasion
por: Elasifer, Hana, et al.
Publicado: (2020)

Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor
por: Fletcher-Etherington, Alice, et al.
Publicado: (2020)

Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries
por: Karniely, S., et al.
Publicado: (2016)

Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex
por: Nightingale, Katie, et al.
Publicado: (2022)

Human Cytomegalovirus Genomes Sequenced Directly From Clinical Material: Variation, Multiple-Strain Infection, Recombination, and Gene Loss
por: Suárez, Nicolás M, et al.
Publicado: (2019)

Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins
por: Beelontally, Rooksarr, et al.
Publicado: (2017)

Human Cytomegalovirus RNA2.7 Is Required for Upregulating Multiple Cellular Genes To Promote Cell Motility and Viral Spread Late in Lytic Infection
por: Lau, Betty, et al.
Publicado: (2021)

Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation
por: Ashley, Caroline L., et al.
Publicado: (2023)

Human Cytomegalovirus Long Non-coding RNA1.2 Suppresses Extracellular Release of the Pro-inflammatory Cytokine IL-6 by Blocking NF-κB Activation
por: Lau, Betty, et al.
Publicado: (2020)

Concerns over functional experiments, interpretation, and required controls
por: Wang, Eddie C.Y., et al.
Publicado: (2022)

Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimens
por: Cunningham, Charles, et al.
Publicado: (2010)

Genome Sequences of Two Pseudorabies Virus Strains Isolated in Greece
por: Papageorgiou, Konstantinos V., et al.
Publicado: (2016)

Controlling Cytomegalovirus: Helping the Immune System Take the Lead
por: Hanley, Patrick J., et al.
Publicado: (2014)

Taking Photographs with a Microscope
por: Maude, Richard J., et al.
Publicado: (2008)

Genomic and biologic comparisons of cyprinid herpesvirus 3 strains
por: Gao, Yuan, et al.
Publicado: (2018)

Genome Sequences of Equid Herpesviruses 2 and 5
por: Wilkie, Gavin S., et al.
Publicado: (2015)

Genotypic analysis of two hypervariable human cytomegalovirus genes
por: Bradley, Amanda J, et al.
Publicado: (2008)

CD200 Receptor Restriction of Myeloid Cell Responses Antagonizes Antiviral Immunity and Facilitates Cytomegalovirus Persistence within Mucosal Tissue
por: Stack, Gabrielle, et al.
Publicado: (2015)

Inhibition of Post-Transcriptional RNA Processing by CDK Inhibitors and Its Implication in Anti-Viral Therapy
por: Holcakova, Jitka, et al.
Publicado: (2014)

Cytomegalovirus Viremia as a Risk Factor for Mortality Prior to Antiretroviral Therapy among HIV-Infected Gold Miners in South Africa
por: Fielding, Katherine, et al.
Publicado: (2011)

Detection of human cytomegalovirus and analysis of strain variation.
por: Huang, E. S., et al.
Publicado: (1976)

Chemical genomics: what will it take and who gets to play?
por: MacBeath, Gavin
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_ob95m1bkk0cjtetrqihgilqrq8