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Endovascular Aneurysm Sealing for the Treatment of Ruptured Abdominal Aortic Aneurysms

Purpose: To assess the feasibility and report preliminary results of ruptured abdominal aortic aneurysm (rAAA) repair with endovascular aneurysm sealing (EVAS), a novel therapeutic alternative whose feasibility has not been established in rAAAs due to the unknown effects of the rupture site on the a...

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Autores principales: de Bruin, Jorg L., Brownrigg, Jack R. W., Karthikesalingam, Alan, Patterson, Benjamin O., Holt, Peter J. E., Hinchliffe, Robert J., Morgan, Robert A., Loftus, Ian M., Thompson, Matthew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439460/
https://www.ncbi.nlm.nih.gov/pubmed/25904491
http://dx.doi.org/10.1177/1526602815582529
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author de Bruin, Jorg L.
Brownrigg, Jack R. W.
Karthikesalingam, Alan
Patterson, Benjamin O.
Holt, Peter J. E.
Hinchliffe, Robert J.
Morgan, Robert A.
Loftus, Ian M.
Thompson, Matthew M.
author_facet de Bruin, Jorg L.
Brownrigg, Jack R. W.
Karthikesalingam, Alan
Patterson, Benjamin O.
Holt, Peter J. E.
Hinchliffe, Robert J.
Morgan, Robert A.
Loftus, Ian M.
Thompson, Matthew M.
author_sort de Bruin, Jorg L.
collection PubMed
description Purpose: To assess the feasibility and report preliminary results of ruptured abdominal aortic aneurysm (rAAA) repair with endovascular aneurysm sealing (EVAS), a novel therapeutic alternative whose feasibility has not been established in rAAAs due to the unknown effects of the rupture site on the ability to achieve sealing. Case Report: Between December 2013 and April 2014, 5 patients (median age 71 years, range 57–90; 3 men) with rAAAs were treated with the Nellix EVAS system at a single institution. Median aneurysm diameter was 70 mm (range 67–91). Aneurysm morphology in 4 of the 5 patients was noncompliant with instructions for use (IFU) for both EVAS and standard stent-grafts; the remaining patient was outside the IFU for standard stent-grafts but treated with EVAS under standard IFU for the Nellix system. Median Hardman index was 2 (range 0–3). Two patients died of multiorgan failure after re-laparotomy and intraoperative cardiac arrest, respectively. Among survivors, all devices were patent with no signs of endoleak or failed aneurysm sac sealing at 6 months (median follow-up 9.2 months). Conclusion: EVAS for the management of infrarenal rAAAs appears feasible. The use of EVAS in emergency repairs may broaden the selection criteria of the current endovascular strategy to include patients with more complex aneurysm morphology.
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spelling pubmed-44394602015-05-31 Endovascular Aneurysm Sealing for the Treatment of Ruptured Abdominal Aortic Aneurysms de Bruin, Jorg L. Brownrigg, Jack R. W. Karthikesalingam, Alan Patterson, Benjamin O. Holt, Peter J. E. Hinchliffe, Robert J. Morgan, Robert A. Loftus, Ian M. Thompson, Matthew M. J Endovasc Ther Endovascular Aneurysm Sealing Purpose: To assess the feasibility and report preliminary results of ruptured abdominal aortic aneurysm (rAAA) repair with endovascular aneurysm sealing (EVAS), a novel therapeutic alternative whose feasibility has not been established in rAAAs due to the unknown effects of the rupture site on the ability to achieve sealing. Case Report: Between December 2013 and April 2014, 5 patients (median age 71 years, range 57–90; 3 men) with rAAAs were treated with the Nellix EVAS system at a single institution. Median aneurysm diameter was 70 mm (range 67–91). Aneurysm morphology in 4 of the 5 patients was noncompliant with instructions for use (IFU) for both EVAS and standard stent-grafts; the remaining patient was outside the IFU for standard stent-grafts but treated with EVAS under standard IFU for the Nellix system. Median Hardman index was 2 (range 0–3). Two patients died of multiorgan failure after re-laparotomy and intraoperative cardiac arrest, respectively. Among survivors, all devices were patent with no signs of endoleak or failed aneurysm sac sealing at 6 months (median follow-up 9.2 months). Conclusion: EVAS for the management of infrarenal rAAAs appears feasible. The use of EVAS in emergency repairs may broaden the selection criteria of the current endovascular strategy to include patients with more complex aneurysm morphology. SAGE Publications 2015-04-22 2015-06 /pmc/articles/PMC4439460/ /pubmed/25904491 http://dx.doi.org/10.1177/1526602815582529 Text en © The Author(s) 2015 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (http://www.uk.sagepub.com/aboutus/openaccess.htm).
spellingShingle Endovascular Aneurysm Sealing
de Bruin, Jorg L.
Brownrigg, Jack R. W.
Karthikesalingam, Alan
Patterson, Benjamin O.
Holt, Peter J. E.
Hinchliffe, Robert J.
Morgan, Robert A.
Loftus, Ian M.
Thompson, Matthew M.
Endovascular Aneurysm Sealing for the Treatment of Ruptured Abdominal Aortic Aneurysms
title Endovascular Aneurysm Sealing for the Treatment of Ruptured Abdominal Aortic Aneurysms
title_full Endovascular Aneurysm Sealing for the Treatment of Ruptured Abdominal Aortic Aneurysms
title_fullStr Endovascular Aneurysm Sealing for the Treatment of Ruptured Abdominal Aortic Aneurysms
title_full_unstemmed Endovascular Aneurysm Sealing for the Treatment of Ruptured Abdominal Aortic Aneurysms
title_short Endovascular Aneurysm Sealing for the Treatment of Ruptured Abdominal Aortic Aneurysms
title_sort endovascular aneurysm sealing for the treatment of ruptured abdominal aortic aneurysms
topic Endovascular Aneurysm Sealing
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439460/
https://www.ncbi.nlm.nih.gov/pubmed/25904491
http://dx.doi.org/10.1177/1526602815582529
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