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Novel Stable Isotope Analyses Demonstrate Significant Rates of Glucose Cycling in Mouse Pancreatic Islets

A polymorphism located in the G6PC2 gene, which encodes an islet-specific glucose-6-phosphatase catalytic subunit, is the most important common determinant of variations in fasting blood glucose (FBG) levels in humans. Studies of G6pc2 knockout (KO) mice suggest that G6pc2 represents a negative regu...

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Detalles Bibliográficos
Autores principales:	Wall, Martha L., Pound, Lynley D., Trenary, Irina, O’Brien, Richard M., Young, Jamey D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2015
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439557/ https://www.ncbi.nlm.nih.gov/pubmed/25552595 http://dx.doi.org/10.2337/db14-0745

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