BAMBI Elimination Enhances Alternative TGF-β Signaling and Glomerular Dysfunction in Diabetic Mice

BMP, activin, membrane-bound inhibitor (BAMBI) acts as a pseudo-receptor for the transforming growth factor (TGF)-β type I receptor family and a negative modulator of TGF-β kinase signaling, and BAMBI(−/−) mice show mild endothelial dysfunction. Because diabetic glomerular disease is associated with...

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Detalles Bibliográficos
Autores principales: Fan, Ying, Li, Xuezhu, Xiao, Wenzhen, Fu, Jia, Harris, Ray C., Lindenmeyer, Maja, Cohen, Clemens D., Guillot, Nicolas, Baron, Margaret H., Wang, Niansong, Lee, Kyung, He, John C., Schlondorff, Detlef, Chuang, Peter Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439561/
https://www.ncbi.nlm.nih.gov/pubmed/25576053
http://dx.doi.org/10.2337/db14-1397

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