Dipeptidyl Peptidase-4 Inhibition Ameliorates Western Diet–Induced Hepatic Steatosis and Insulin Resistance Through Hepatic Lipid Remodeling and Modulation of Hepatic Mitochondrial Function

Novel therapies are needed for treating the increasing prevalence of hepatic steatosis in Western populations. In this regard, dipeptidyl peptidase-4 (DPP-4) inhibitors have recently been reported to attenuate the development of hepatic steatosis, but the potential mechanisms remain poorly defined....

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Detalles Bibliográficos
Autores principales: Aroor, Annayya R., Habibi, Javad, Ford, David A., Nistala, Ravi, Lastra, Guido, Manrique, Camila, Dunham, Merlow M., Ford, Kaitlin D., Thyfault, John P., Parks, Elizabeth J., Sowers, James R., Rector, R. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439570/
https://www.ncbi.nlm.nih.gov/pubmed/25605806
http://dx.doi.org/10.2337/db14-0804

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