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TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching

The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family. Here we present the structure of the Caenorhabditis elegans TRIP13 ortholog PCH-2, revealing a new family of AAA+ ATPase p...

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Detalles Bibliográficos
Autores principales:	Ye, Qiaozhen, Rosenberg, Scott C, Moeller, Arne, Speir, Jeffrey A, Su, Tiffany Y, Corbett, Kevin D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439613/ https://www.ncbi.nlm.nih.gov/pubmed/25918846 http://dx.doi.org/10.7554/eLife.07367

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