Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant

Acute megakaryoblastic leukemia (AMKL) with t(1;22) (p13;q13) is an extremely rare subtype of acute myeloid leukemia that is almost always described in infants. t(1;22) (p13;q13)-positive AMKL with extramedullary infiltration has been previously reported only once in the literature. Herein, we repor...

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Detalles Bibliográficos
Autores principales: Gökçe, Müge, Aytaç, Selin, Ünal, Şule, Altan, İlhan, Gümrük, Fatma, Çetin, Mualla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439909/
https://www.ncbi.nlm.nih.gov/pubmed/25805677
http://dx.doi.org/10.4274/tjh.2013.0189
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author Gökçe, Müge
Aytaç, Selin
Ünal, Şule
Altan, İlhan
Gümrük, Fatma
Çetin, Mualla
author_facet Gökçe, Müge
Aytaç, Selin
Ünal, Şule
Altan, İlhan
Gümrük, Fatma
Çetin, Mualla
author_sort Gökçe, Müge
collection PubMed
description Acute megakaryoblastic leukemia (AMKL) with t(1;22) (p13;q13) is an extremely rare subtype of acute myeloid leukemia that is almost always described in infants. t(1;22) (p13;q13)-positive AMKL with extramedullary infiltration has been previously reported only once in the literature. Herein, we report a 3-month-old infant presenting with a pelvic mass and pancytopenia suggesting neuroblastoma. Bone marrow evaluation revealed t(1;22)-positive AMKL that responded well to a regimen containing high-dose cytarabine.
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spelling pubmed-44399092016-01-20 Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant Gökçe, Müge Aytaç, Selin Ünal, Şule Altan, İlhan Gümrük, Fatma Çetin, Mualla Turk J Haematol Case Report Acute megakaryoblastic leukemia (AMKL) with t(1;22) (p13;q13) is an extremely rare subtype of acute myeloid leukemia that is almost always described in infants. t(1;22) (p13;q13)-positive AMKL with extramedullary infiltration has been previously reported only once in the literature. Herein, we report a 3-month-old infant presenting with a pelvic mass and pancytopenia suggesting neuroblastoma. Bone marrow evaluation revealed t(1;22)-positive AMKL that responded well to a regimen containing high-dose cytarabine. Galenos Publishing 2015-03 2015-02-15 /pmc/articles/PMC4439909/ /pubmed/25805677 http://dx.doi.org/10.4274/tjh.2013.0189 Text en © Turkish Journal of Hematology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gökçe, Müge
Aytaç, Selin
Ünal, Şule
Altan, İlhan
Gümrük, Fatma
Çetin, Mualla
Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant
title Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant
title_full Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant
title_fullStr Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant
title_full_unstemmed Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant
title_short Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant
title_sort acute megakaryoblastic leukemia with t(1;22) mimicking neuroblastoma in an infant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439909/
https://www.ncbi.nlm.nih.gov/pubmed/25805677
http://dx.doi.org/10.4274/tjh.2013.0189
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