Successful Off-Label Use of Recombinant Factor VIIa and Coil Embolization in an Adolescent with Massive Hemoptysis Due to Invasive Pulmonary Aspergillosis

Invasive fungal infections have turned out to be a significant cause of morbidity and mortality in pediatric patients with malignant disorders. Massive hemoptysis, a rare complication of invasive pulmonary aspergillosis, may threaten the lives of patients, usually during the resolution of neutropeni...

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Autores principales: Gürlek Gökçebay, Dilek, Fettah, Ali, Kırbaş, İsmail, Tunç, Bahattin, Özbek, Namık Yaşar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439911/
https://www.ncbi.nlm.nih.gov/pubmed/25805679
http://dx.doi.org/10.4274/tjh.2014.0347
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author Gürlek Gökçebay, Dilek
Fettah, Ali
Kırbaş, İsmail
Tunç, Bahattin
Özbek, Namık Yaşar
author_facet Gürlek Gökçebay, Dilek
Fettah, Ali
Kırbaş, İsmail
Tunç, Bahattin
Özbek, Namık Yaşar
author_sort Gürlek Gökçebay, Dilek
collection PubMed
description Invasive fungal infections have turned out to be a significant cause of morbidity and mortality in pediatric patients with malignant disorders. Massive hemoptysis, a rare complication of invasive pulmonary aspergillosis, may threaten the lives of patients, usually during the resolution of neutropenia. In this report, we describe a patient with massive hemoptysis due to invasive pulmonary aspergillosis whose bleeding was controlled successfully with off-label use of recombinant factor VIIa and subsequent coil embolization of the right pulmonary artery.
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spelling pubmed-44399112016-01-20 Successful Off-Label Use of Recombinant Factor VIIa and Coil Embolization in an Adolescent with Massive Hemoptysis Due to Invasive Pulmonary Aspergillosis Gürlek Gökçebay, Dilek Fettah, Ali Kırbaş, İsmail Tunç, Bahattin Özbek, Namık Yaşar Turk J Haematol Case Report Invasive fungal infections have turned out to be a significant cause of morbidity and mortality in pediatric patients with malignant disorders. Massive hemoptysis, a rare complication of invasive pulmonary aspergillosis, may threaten the lives of patients, usually during the resolution of neutropenia. In this report, we describe a patient with massive hemoptysis due to invasive pulmonary aspergillosis whose bleeding was controlled successfully with off-label use of recombinant factor VIIa and subsequent coil embolization of the right pulmonary artery. Galenos Publishing 2015-03 2015-02-15 /pmc/articles/PMC4439911/ /pubmed/25805679 http://dx.doi.org/10.4274/tjh.2014.0347 Text en © Turkish Journal of Hematology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gürlek Gökçebay, Dilek
Fettah, Ali
Kırbaş, İsmail
Tunç, Bahattin
Özbek, Namık Yaşar
Successful Off-Label Use of Recombinant Factor VIIa and Coil Embolization in an Adolescent with Massive Hemoptysis Due to Invasive Pulmonary Aspergillosis
title Successful Off-Label Use of Recombinant Factor VIIa and Coil Embolization in an Adolescent with Massive Hemoptysis Due to Invasive Pulmonary Aspergillosis
title_full Successful Off-Label Use of Recombinant Factor VIIa and Coil Embolization in an Adolescent with Massive Hemoptysis Due to Invasive Pulmonary Aspergillosis
title_fullStr Successful Off-Label Use of Recombinant Factor VIIa and Coil Embolization in an Adolescent with Massive Hemoptysis Due to Invasive Pulmonary Aspergillosis
title_full_unstemmed Successful Off-Label Use of Recombinant Factor VIIa and Coil Embolization in an Adolescent with Massive Hemoptysis Due to Invasive Pulmonary Aspergillosis
title_short Successful Off-Label Use of Recombinant Factor VIIa and Coil Embolization in an Adolescent with Massive Hemoptysis Due to Invasive Pulmonary Aspergillosis
title_sort successful off-label use of recombinant factor viia and coil embolization in an adolescent with massive hemoptysis due to invasive pulmonary aspergillosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439911/
https://www.ncbi.nlm.nih.gov/pubmed/25805679
http://dx.doi.org/10.4274/tjh.2014.0347
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