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Effect of oral administration of kynurenic acid on the activity of the peripheral blood leukocytes in mice

Kynurenic acid (KYNA), an endogenous tryptophan metabolite, is a selective ligand of the GPR35 receptor, expressed mainly on the immune cells. In inflammatory conditions, by affecting this receptor, KYNA inhibits the synthesis of pro-inflammatory cytokines and probably protects tissues from oxidativ...

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Detalles Bibliográficos
Autores principales:	Małaczewska, Joanna, Siwicki, Andrzej Krzysztof, Wójcik, Roman Marcin, Kaczorek, Edyta, Turski, Waldemar Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Polish Society of Experimental and Clinical Immunology 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439973/ https://www.ncbi.nlm.nih.gov/pubmed/26155092 http://dx.doi.org/10.5114/ceji.2014.42115

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