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Diet-induced obesity mediates a proinflammatory response in pancreatic β cell via toll-like receptor 4

Toll-like receptor 4 has an important role in inflammation and immunity. Whether TLR4 signaling contributes to the link between insulin resistance and islet β cell dysfunction is an unanswered question. Here, we show that in the face of the same high-fat continuous stimulation for 24 weeks, in TLR4–...

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Detalles Bibliográficos
Autores principales: Li, Juan, Chen, Shufen, Qiang, Juan, Wang, Xin, Chen, Lei, Zou, Dajin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish Society of Experimental and Clinical Immunology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439999/
https://www.ncbi.nlm.nih.gov/pubmed/26155140
http://dx.doi.org/10.5114/ceji.2014.45940

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