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Reactive oxygen species promote ovarian cancer progression via the HIF-1α/LOX/E-cadherin pathway

Reactive oxygen species (ROS) can drive the de-differentiation of tumor cells leading to the process of epithelial-to-mesenchymal transition (EMT) to enhance invasion and metastasis. The invasive and metastatic phenotype of malignant cells is often linked to loss of E-cadherin expression, a hallmark...

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Detalles Bibliográficos
Autores principales:	WANG, YU, MA, JUN, SHEN, HAORAN, WANG, CHENGJIE, SUN, YUEPING, HOWELL, STEPHEN B., LIN, XINJIAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440217/ https://www.ncbi.nlm.nih.gov/pubmed/25174950 http://dx.doi.org/10.3892/or.2014.3448

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