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The Oncogenic MicroRNA miR-21 Promotes Regulated Necrosis in Mice
MicroRNAs (miRNAs) regulate apoptosis, yet their role in regulated necrosis remains unknown. miR-21 is overexpressed in nearly all human cancer types and its role as an oncogene is suggested to largely depend on its anti-apoptotic action. Here we show that miR-21 is overexpressed in a murine model o...
Autores principales: | Ma, Xiaodong, Conklin, Daniel J., Li, Fenge, Dai, Zhongping, Hua, Xiang, Li, Yan, Xu-Monette, Zijun Y., Young, Ken H., Xiong, Wei, Wysoczynski, Marcin, Sithu, Srinivas D., Srivastava, Sanjay, Bhatnagar, Aruni, Li, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440243/ https://www.ncbi.nlm.nih.gov/pubmed/25990308 http://dx.doi.org/10.1038/ncomms8151 |
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