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Novel Genome-Editing Tools to Model and Correct Primary Immunodeficiencies

Severe combined immunodeficiency (SCID) and other severe non-SCID primary immunodeficiencies (non-SCID PID) can be treated by allogeneic hematopoietic stem cell (HSC) transplantation, but when histocompatibility leukocyte antigen-matched donors are lacking, this can be a high-risk procedure. Correct...

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Detalles Bibliográficos
Autores principales: Ott de Bruin, Lisa M., Volpi, Stefano, Musunuru, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440404/
https://www.ncbi.nlm.nih.gov/pubmed/26052330
http://dx.doi.org/10.3389/fimmu.2015.00250