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Novel Genome-Editing Tools to Model and Correct Primary Immunodeficiencies
Severe combined immunodeficiency (SCID) and other severe non-SCID primary immunodeficiencies (non-SCID PID) can be treated by allogeneic hematopoietic stem cell (HSC) transplantation, but when histocompatibility leukocyte antigen-matched donors are lacking, this can be a high-risk procedure. Correct...
Autores principales: | Ott de Bruin, Lisa M., Volpi, Stefano, Musunuru, Kiran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440404/ https://www.ncbi.nlm.nih.gov/pubmed/26052330 http://dx.doi.org/10.3389/fimmu.2015.00250 |
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