DNA stabilization by the upregulation of estrogen signaling in BRCA gene mutation carriers

Currently available scientific evidence erroneously suggests that mutagenic weakness or loss of the BRCA1/2 genes may liberate the proliferative effects of estrogen signaling, which provokes DNA damage and genomic instability. Conversely, BRCA mutation seems to be an imbalanced defect, crudely inhib...

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Detalles Bibliográficos
Autor principal: Suba, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440422/
https://www.ncbi.nlm.nih.gov/pubmed/26028963
http://dx.doi.org/10.2147/DDDT.S84437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440422/
https://www.ncbi.nlm.nih.gov/pubmed/26028963
http://dx.doi.org/10.2147/DDDT.S84437

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