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DNA stabilization by the upregulation of estrogen signaling in BRCA gene mutation carriers
Currently available scientific evidence erroneously suggests that mutagenic weakness or loss of the BRCA1/2 genes may liberate the proliferative effects of estrogen signaling, which provokes DNA damage and genomic instability. Conversely, BRCA mutation seems to be an imbalanced defect, crudely inhib...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440422/ https://www.ncbi.nlm.nih.gov/pubmed/26028963 http://dx.doi.org/10.2147/DDDT.S84437 |