Development of two novel high-throughput assays to quantify ubiquitylated proteins in cell lysates: application to screening of new anti-malarials

BACKGROUND: The ubiquitin proteasome system (UPS) is one of the main proteolytical pathways in eukaryotic cells and plays an essential role in key cellular processes such as cell cycle, stress response, signal transduction, and transcriptional regulation. Many components of this pathway have been im...

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Detalles Bibliográficos
Autores principales: Mata-Cantero, Lydia, Cid, Concepción, Gomez-Lorenzo, Maria G, Xolalpa, Wendy, Aillet, Fabienne, Martín, J Julio, Rodriguez, Manuel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440562/
https://www.ncbi.nlm.nih.gov/pubmed/25968882
http://dx.doi.org/10.1186/s12936-015-0708-1

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