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Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects
BACKGROUND: The inflammatory mediator lipopolysaccharide (LPS) has been shown to induce acute gliosis in neonatal mice. However, the progressive effects on the murine neurodevelopmental program over the week that follows systemic inflammation are not known. Thus, we investigated the effects of repea...
Autores principales: | Cardoso, Filipa L, Herz, Jasmin, Fernandes, Adelaide, Rocha, João, Sepodes, Bruno, Brito, Maria A, McGavern, Dorian B, Brites, Dora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440597/ https://www.ncbi.nlm.nih.gov/pubmed/25924675 http://dx.doi.org/10.1186/s12974-015-0299-3 |
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