Immunogenicity without Efficacy of an Adenoviral Tuberculosis Vaccine in a Stringent Mouse Model for Immunotherapy during Treatment

To investigate if bacterial persistence during TB drug treatment could be overcome by modulation of host immunity, we adapted a clinically-relevant model developed for the evaluation of new drugs and examined if immunotherapy with two adenoviral vaccines, Ad35-TBS (AERAS-402) and Ad26-TBS, could sho...

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Detalles Bibliográficos
Autores principales: Alyahya, S. Anisah, Nolan, Scott T., Smith, Cara M. R., Bishai, William R., Sadoff, Jerald, Lamichhane, Gyanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440646/
https://www.ncbi.nlm.nih.gov/pubmed/25996375
http://dx.doi.org/10.1371/journal.pone.0127907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440646/
https://www.ncbi.nlm.nih.gov/pubmed/25996375
http://dx.doi.org/10.1371/journal.pone.0127907

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