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Clustering and Negative Feedback by Endocytosis in Planar Cell Polarity Signaling Is Modulated by Ubiquitinylation of Prickle

The core components of the planar cell polarity (PCP) signaling system, including both transmembrane and peripheral membrane associated proteins, form asymmetric complexes that bridge apical intercellular junctions. While these can assemble in either orientation, coordinated cell polarization requir...

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Detalles Bibliográficos
Autores principales: Cho, Bomsoo, Pierre-Louis, Gandhy, Sagner, Andreas, Eaton, Suzanne, Axelrod, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440771/
https://www.ncbi.nlm.nih.gov/pubmed/25996914
http://dx.doi.org/10.1371/journal.pgen.1005259