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Clustering and Negative Feedback by Endocytosis in Planar Cell Polarity Signaling Is Modulated by Ubiquitinylation of Prickle
The core components of the planar cell polarity (PCP) signaling system, including both transmembrane and peripheral membrane associated proteins, form asymmetric complexes that bridge apical intercellular junctions. While these can assemble in either orientation, coordinated cell polarization requir...
Autores principales: | Cho, Bomsoo, Pierre-Louis, Gandhy, Sagner, Andreas, Eaton, Suzanne, Axelrod, Jeffrey D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440771/ https://www.ncbi.nlm.nih.gov/pubmed/25996914 http://dx.doi.org/10.1371/journal.pgen.1005259 |
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