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Turning Saccharomyces cerevisiae into a Frataxin-Independent Organism

Frataxin (Yfh1 in yeast) is a conserved protein and deficiency leads to the neurodegenerative disease Friedreich’s ataxia. Frataxin is a critical protein for Fe-S cluster assembly in mitochondria, interacting with other components of the Fe-S cluster machinery, including cysteine desulfurase Nfs1, I...

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Detalles Bibliográficos
Autores principales:	Yoon, Heeyong, Knight, Simon A. B., Pandey, Alok, Pain, Jayashree, Turkarslan, Serdar, Pain, Debkumar, Dancis, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440810/ https://www.ncbi.nlm.nih.gov/pubmed/25996596 http://dx.doi.org/10.1371/journal.pgen.1005135

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